What is Medical Ozone Therapy?

Ozone is a chemical compound consisting of three oxygen atoms O3 (i.e. triatomic oxygen), a highly energetic form of normal (diatomic) atmospheric oxygen (O2). Due to it being an extremely powerful oxidizing agent and a highly effective disinfectant, it is used throughout the world to destroy germs in water treatment installations supplying drinking water. Medical ozone is prepared from pure medical oxygen via silent electrical discharge for use as an ozone/oxygen mixture at an exact concentration and dosage.

CALL 480-551-9000 TO

History behind Ozone Therapy

The first use of ozone intravenously was done in the 1940s and its development is credited to Dr. H. Wolff. It is the most common ozone treatment today and is used by thousands of physicians worldwide in countries like Germany, Poland, Egypt, Austria, Switzerland, Italy, France, England, Canada, Russia, India, Eastern Europe, Cuba and Mexico.

How does Medical Ozone Therapy work?

Research shows that Ozone has highly pronounced anti-bacterial, anti-viral and anti-fungal properties. Ozone’s ability to stimulate circulation is beneficial in the treatment of various circulatory disorders and makes it valuable in revitalizing organic functions. Ozone is a potent regulator of the immune system. This unique property makes the therapy effective in both over and under active immune systems. Ozone also activates the body’s own antioxidant systems and free radical scavengers by stimulating glutathione and superoxide dismutase and is thus useful in diseases that involve chronic inflammation and mitochondrial dysfunction.

Summary of Ozone Therapy benefits:

  1. Increases oxygen delivery to cells, tissues, and organs
  2. Increases blood circulation throughout the body
  3. Detoxification
  4. Activates and modulates the immune system
  5. Accelerates wound healing

Indications for treatment:

  1. Circulatory disorders (atherosclerosis, peripheral artery disease (PAD), neuropathy)
  2. Autoimmune disease (Lupus, RA, Fibromyalgia, Chronic Fatigue Syndrome)
  3. Viral disease (Herpes, Hepatitis, EBV, CMV, Influenza, etc.)
  4. Treatment of poorly healing wounds and inflammatory processes
  5. Complementary therapy to cancer
  6. General fatigue, revitalization and anti-aging
  7. Diseases of the eye
  8. Intestinal disease (Crohn’s disease and Ulcerative colitis)
  9. Inflammatory and degenerative Joints
  10. Detoxification

Why is Medical Ozone Therapy not more widely used?

There is very little incentive for studying ozone therapy due to the inability to patent the process. Any physician with knowledge and proper training can obtain an oxygen tank and ozone generator to perform the treatments. Also, because of ozone’s ability to potentially treat such a vast range of illnesses the economic impact could be huge if it could replace more expensive therapies with minimal to no side-effects.

Routes of Medical Ozone Administration

Major Autohemotherapy

Major autohemotherapy (treatment of the patient’s blood outside the body before reinfusion) is useful for revitalization, in the treatment of circulatory disorders, virus-producing diseases, general immunoactivation and in geriatrics (age-related conditions).
 By this method, 100 to 150 ml of the patient’s own blood is withdrawn in a sterile setting and enriched externally with a specific amount of ozone. The ozone reacts completely – i.e. at a rate of 100 % – with specific substances making up the red and white blood cells and activates their vital activities = metabolism. It is this activated blood (not ozone or oxygen!) that is immediately reintroduced into the patient’s system using a normal drip unit.

Minor Autohemotherapy

Minor autohemotherapy is an intramuscular injection of the patient’s blood with ozone for nonspecific immunoactivation and revitalization. This method can be used for allergies or in a general way to improve the body’s inherent resistance to physical and mental stress.

Colon Insufflation

Ozone application via the rectal route is not as inconvenient or unpleasant as it sounds (medically, it is called insufflation). In fact, the patient feels absolutely nothing, as the ozone is directly absorbed by the sensitive intestinal membranes; in addition, the specially designed disposable tube is lubricated, which makes the method hygienic and practical, as a patient can apply it himself/herself. This method is primarily indicated for inflammatory conditions of the intestinal tract, but is finding increasing use for general revitalization processes.


Ozone is carefully injected for the treatment of inflamed and painful joints or herniated discs (arthritis, recurrent arthrosis, general pathological stiffness) to help heal damaged tissue.

Topical Application

External treatment is primarily achieved through a closed system using O3 gas fed into plastic “boots” (for the legs and feet) fitting various parts of the body. This method is highly effective in treating ulcers, sores, open wounds, postoperative lesions, shingles (herpes) and infected areas etc. Other topical methods of application are ozonated water and ozonated olive oil (for skin eruptions such as eczemas, acne, and conditions involving molds, funguses and lichens etc.).

Ozone Therapy and the FDA

Rejuvena Health and Aesthetics, LLC is not offering ozone therapy as a cure for any condition, disease, or injury. No statements or treatments on this website have been evaluated or approved by the FDA. This website contains no medical advice. All statements and opinions on this website are provided for educational and informational purposes only. We do not diagnose or treat via this website. Our center is offering patient-funded research to treat individuals with autologous (their own) blood ozone and is not involved in the use or manufacture of any investigational drugs.

Rejuvena Health and Aesthetics, LLC does not claim that any applications, or potential applications, using autologous ozone therapy treatments are approved by the FDA, or are even effective. We do not claim that these treatments work for any listed nor unlisted condition, intended or implied. It is important for potential patients to do their own research based on the options that we present so they can make informed decisions. Any decision to participate in our patient-funded experimental protocols is completely voluntary.